Pediatric Clinical Trials

Joining a Trial

Choosing to participate in a clinical trial is an important personal decision. It is often helpful to talk to a physician, family members, or friends about deciding to join a trial. After identifying some trial options, the next step is to contact the study research staff and ask questions about specific trials.

A listing of our current clinical trials is below or you can call the Office of Clinical Research to learn more.

Current clinical trials:

  • AstraZenaca CV181375 D1680C00019 – A 26 Week, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Phase 3 Trial with a 26 Week Safety Extension Period Evaluating the Safety and Efficacy of Dapagliflozin 5 and 10 mg, and Saxagliptin 2.5 and 5 mg in Pediatric Patients with Type 2 Diabetes Mellitus Who Are Between 10 and Below 18 Years of Age
  • Otsuka 331-10-234 – A Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial to Evaluate the Efficacy of Brexpiprazole Monotherapy for the Treatment in Adolescents (13-17 years old) With Schizophrenia
  • PCORI MOBILITY – Metformin for Overweight & Obese Children and Adolescents With Bipolar Spectrum Disorders Treated With Second-Generation Antipsychotics
  • Shire SPD489-347 – A Phase 3, Randomized, Double-blind, Multicenter, Parallel-group, Placebo-controlled, Fixed-dose Safety and Efficacy Study of SPD489 Compared with Placebo in Preschool Children Aged 4-5 Years with Attention-deficit/Hyperactivity Disorder
  • Shire SPD489-348 – Phase 3, Open-label, Multicenter, 12-Month Safety and Tolerability Study of SPD489 in Preschool Children Aged 4-5 Years Diagnosed with Attention-deficit/Hyperactivity Disorder

Contact the Office of Clinical Research

Phone: 732-776-2953

What is a clinical trial?

A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions which can help determine if a medication or a treatment regimen is safe and effective for treating a specific condition or disease. Clinical trials compare the effectiveness of the study medication or treatment against standard, accepted treatment or against a placebo, if no standard treatment exists.

What to expect if admitted to a trial
If you are accepted and consent to participate in a clinical trial, you will be given a structured program to follow. You may have a schedule of tests, doctors’ appointments, and treatments. You may also be asked to keep a diary of your experience during this time. It is important to carefully follow directions.

Doctors, nurses, social workers, and other health professionals may be part of your treatment team. Your treatment team may continue to check on you after your trial is over.

Why participate in a clinical trial?
Participants in clinical trials can play a more active role in their own health care, gain access to new research treatments before they are widely available, and help others by contributing to medical research.

If you have more questions or want to find other trials visit ClinicalTrials.gov which provides regularly updated information about federally and privately supported clinical research in human volunteers. ClinicalTrials.gov gives you information about a trial’s purpose, who may participate, locations, and phone numbers for more details.

To learn more about our Clinical Trial Program, download our brochure Understanding Clinical Research