Calcifications Seen in Blood Vessels on Mammograms May Predict Stroke

In addition to detecting breast cancer in its early stages, new research suggests that mammograms may also help predict which women are at risk for strokes, say researchers at the American Stroke Association International Stroke Conference.

Calcifications found in the blood vessels of the breasts — what physicians call benign arterial calcifications — were more commonly found on the mammograms of women who had suffered a stroke, says Dr. Paul S. Dale at the University of Missouri.

Stroke is the third leading cause of death for women over 40, says Dr. Dale.

Previous studies, including some by the University of Missouri team, have found a link between these calcifications, which are not cancerous, and the risk of diabetes, heart disease, and stroke. But Dr. Dale says he believes this latest study has found an even stronger association.

Women with Strokes Had Calcification
In all, they looked at 793 mammograms of women ages 40 to 90. On the screening mammograms, 86 of the 793 women, or about 10 percent, had the calcifications. But 115 of the 204 women in the group who had had a stroke had the calcifications.

"Of those who had a stroke, 56 percent of them had these calcifications on their mammograms, compared to about 10 percent of women in the general population," says Dr. Dale.

"The important thing here is, we adjusted for age, because age increases your risk of stroke and also of having calcifications on your mammogram," he says.

While the finding is not brand new, it is interesting, notes Dr. Suzanne Steinbaum at the Heart and Vascular Institute at Lenox Hill Hospital in New York City.

"There have been other studies to show this," she says. "As a cardiologist, I would love this information."

Findings Should Be Shared, Doctors Say
It is one more piece of information, says Dr. Steinbaum, that could potentially help inform doctors about a woman's risk for cardiovascular disease.

If she got a mammogram from a patient with that information, she says, "It would lead me to believe I need to screen this woman for cardiovascular disease."

Dr. Dale's team is continuing to study the link between the calcifications and cardiovascular diseases and diabetes.

It is probably too soon, he says, to advise women to ask their physician if they have calcifications on the mammogram. After more research is done, that might be a consumer-savvy step.

Always consult your physician for more information.

Online Resources

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American College of Radiology

American Heart Association

American Stroke Association

National Breast Cancer Coalition

National Institute of Neurological Disorders and Stroke

National Stroke Association