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Metabolic Syndrome
Addressed with Moderate Exercise

A brisk 30-minute walk most days of the week is enough to undo metabolic syndrome, a health condition that can lead to heart disease, diabetes, and stroke, according to a report in the American Journal of Cardiology.

Metabolic Syndrome Addressed with Moderate Exercise

"What we found was a modest amount of moderate intensity exercise was very effective in improving metabolic syndrome risk," says study author Johanna L. Johnson, MS, a clinical researcher at Duke University Medical Center.

At the start of the study, 41 percent of the 171 participants had metabolic syndrome; at the end, just 27 percent did.

About one-quarter of all US adults have metabolic syndrome, a collection of risk factors that can eventually set you up for more serious health problems.

While some experts debate the validity of considering metabolic syndrome a disease unto itself, the risk factors are potentially dangerous.

They include a large waist circumference; high blood pressure; high levels of triglycerides; low levels of good (HDL) cholesterol; and high blood sugar. When three or more of the five risk factors are present, a person is considered to have metabolic syndrome.

Regular, Steady Exercise a Benefit
The researchers assigned the 171 men and women to one of four groups, so that the effects of different amounts and intensities of exercise could be studied.

The groups were:

  • A control group, whose members continued to be sedentary.


  • A low amount/moderate intensity group. They did brisk walking three to five days a week, aiming for about 11 miles, and typically putting in about three hours a week.


  • A low amount/vigorous intensity group. They did the same 11 or so miles but at a jogging pace, so they ended up getting about two hours of exercise a week.


  • A high amount/vigorous intensity group. They jogged at a vigorous pace about 17 miles a week, putting in about three hours.

What was a bit surprising, Johnson says, was the benefits conferred to each group.

"What we found was that modest amounts of moderate intensity exercise [the low/moderate group] were very effective in improving metabolic syndrome," she notes.

Those who exercised the most, jogging 17 miles a week, gained a bit more benefit in terms of lowered metabolic syndrome scores.

Those in the low amount/vigorous intensity group did not improve their scores as much as those who did less-intense exercise for a longer period of time (the low amount/moderate intensity group).

Moderate intensity activity every day, or almost every day, may be better for metabolic syndrome risk reduction than more vigorous activity a few days a week, the researchers suggest.

All three groups of exercisers did have a reduction in their waistline circumference. Waist circumferences above 34.6 inches in women and 40.2 in men are a risk factor for metabolic syndrome.

The high amount/vigorous intensity group had the best reduction in body mass index (BMI, a ratio of weight to height). It went from an average of 29.2 to 28.4. A BMI of 30 and higher is termed obese.

30 Minutes, Four or Five Days a Week
So, the bottom line for middle-age, sedentary, overweight people?

"If you tell them to go out for a brisk walk 30 minutes on most days of the week, they are highly likely to improve health and metabolic syndrome risk," says Johnson.

The new research confirms advice on exercise from the American College of Sports Medicine and the Centers for Disease Control and Prevention (CDC), she adds.

"It confirms that exercise is beneficial," says Dr. Kerry Stewart, a professor of medicine at Johns Hopkins University School of Medicine.

"It confirms the benefit of exercise for reducing metabolic syndrome and all the risk factors that make up metabolic syndrome," he says. The surprise, he agrees, was that moderate activity may be enough.

Always consult your physician for more information.

February 2008

Metabolic
Syndrome Defined

Metabolic syndrome is a condition that includes the presence of a cluster of risk factors specific for cardiovascular disease.

Metabolic syndrome significantly raises the risk of developing diabetes, heart disease, and/or stroke.

Most people who have metabolic syndrome have insulin resistance.

The body makes insulin to move glucose (sugar) into cells for use as energy.

Obesity, commonly found in persons with metabolic syndrome, makes it more difficult for cells to respond to insulin.

If the body cannot make enough insulin to override the resistance, the blood sugar level increases and diabetes can result. Metabolic syndrome may be a beginning of the development of type 2 diabetes.

Because metabolic syndrome and insulin resistance are closely associated, many healthcare professionals believe that insulin resistance may be a cause of metabolic syndrome.

However, a direct link between the two conditions has not been established.

Others believe that hormone changes, caused by chronic stress, lead to the development of abdominal obesity, insulin resistance, and elevated blood lipids (triglycerides and cholesterol).

Other factors which are thought to contribute to the development of metabolic syndrome include genetic variations in a person's ability to break down lipids (fats) in the blood, older age, and abnormalities in the distribution of body fat.

Risk factors most closely associated with metabolic syndrome include:

  • age - the incidence of metabolic syndrome increases with age


  • ethnicity - African Americans and Mexican Americans are more prone to metabolic syndrome. African-American women are about 60 percent more likely than African-American men to have the syndrome.


  • body mass index (BMI) greater than 25 - the BMI is calculated as a measure of body fat compared to height and weight.


  • personal or family history of diabetes - there is a greater risk for metabolic syndrome for those who have experienced diabetes during pregnancy (gestational diabetes) or who have a family member with type 2 diabetes.


  • smoking


  • history of heavy drinking


  • stress


  • post-menopausal status


  • high-fat diet


  • sedentary lifestyle

Always consult your physician for more information.


Online Resources

(Our Organization is not responsible for the content of Internet sites.)

AHA - Choose To Move

American Academy of Family Physicians - Exercise: A Healthy Habit to Start and Keep

American Council on Exercise

American Heart Association - Just Move Program

American Journal of Cardiology - Exercise Training Amount and Intensity Effects on Metabolic Syndrome (from Studies of a Targeted Risk Reduction Intervention through Defined Exercise)

CDC - Physical Activity

National Heart, Lung, and Blood Institute (NHLBI)


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